✦ LIBER ✦

Introduction to the physics of molecular imaging with radioactive tracers in small animals

✍ Scribed by Michael A. King; P. Hendrik Pretorius; Troy Farncombe; Freek J. Beekman

Publisher: John Wiley and Sons
Year: 2002
Tongue: English
Weight: 320 KB
Volume: 87
Category: Article
ISSN: 0730-2312
DOI: 10.1002/jcb.10447

No coin nor oath required. For personal study only.

✦ Synopsis

Recent advances have greatly enhanced the three-dimensional (3D) imaging of radioactive tracers in living animals. this article introduces the physics of imaging behind the imaging methods. The article first discusses the selection of the radiation emitted from the tracer and then the process of tomographic reconstruction or how 3D images are made from imaging around the outside of the animal. The technique of single photon emission computed tomography (SPECT) in which the detection of one X-ray or gamma ray at a time is employed for image formation is then described. Finally, positron emission tomography (PET) which relies on the simultaneous detection of the pair of gamma-rays formed when the positron annihilates is presented.

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