Introduction to Evolutionary Genomics

✍ Scribed by Naruya Saitou (auth.)

• Publisher: Springer-Verlag London
• Year: 2013
• Tongue: English
• Leaves: 476
• Series: Computational Biology 17
• Edition: 1
• Category: Library

✦ Synopsis

This book is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Features: introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection; presents a brief evolutionary history of life from the primordial seas to the emergence of humans; describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans; reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building; discusses databases of genome sequences and related information, evolutionary distances, and population genomics; provides supplementary material at an associated website.

✦ Table of Contents

Front Matter....Pages i-xxiii
Front Matter....Pages 1-1
Basic Metabolism Surrounding DNAs....Pages 3-26
Mutation....Pages 27-54
Phylogeny....Pages 55-87
Neutral Evolution....Pages 89-124
Natural Selection....Pages 125-154
Front Matter....Pages 155-155
A Brief History of Life....Pages 157-173
Prokaryote Genomes....Pages 175-191
Eukaryote Genomes....Pages 193-222
Vertebrate Genomes....Pages 223-247
Human Genome....Pages 249-262
Front Matter....Pages 263-263
Genome Sequencing....Pages 265-280
Omic Data Collection....Pages 281-288
Databases....Pages 289-299
Sequence Homology Handling....Pages 301-334
Evolutionary Distances....Pages 335-366
Tree and Network Building....Pages 367-415
Population Genomics....Pages 417-442
Back Matter....Pages 443-461

✦ Subjects

Computational Biology/Bioinformatics; Systems Biology; Microbial Genetics and Genomics; Plant Genetics & Genomics; Animal Genetics and Genomics