Quantifying biological specificity: The
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Joรซl Janin
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Article
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1996
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John Wiley and Sons
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English
โ 678 KB
The Random Energy Model of statistical physics is applied to the problem of the specificity of recognition between two biological (macro)molecules forming a non-covalent complex. In this model, the native mode of association is separated by an energy gap from a large body of non-native modes. Wherea