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Introduction: Irinotecan in brain tumors

✍ Scribed by Henry S. Friedman

Book ID: 102107376
Publisher: John Wiley and Sons
Year: 2003
Tongue: English
Weight: 34 KB
Volume: 97
Category: Article
ISSN: 0008-543X
DOI: 10.1002/cncr.11303

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Irinotecan is a water-soluble derivative of camptothecin, an alkylator originally extracted from the Chinese tree Camptotheca acuminata. Laboratory studies have demonstrated the activity of irinotecan in a broad panel of pediatric and adult central nervous system tumor xenografts in athymic nude mic