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Introducing the Levinthal’s Protein Folding Paradox and Its Solution

✍ Scribed by Martínez, Leandro

Book ID
125848519
Publisher
American Chemical Society
Year
2014
Tongue
English
Weight
520 KB
Volume
91
Category
Article
ISSN
0021-9584

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## Abstract Most proteins encoded by the nuclear genome are synthesized in the cytoplasm and fold into precise 3D structures. During synthesis, the nascent polypeptide begins to fold as it traverses the large subunit of the ribosome and is assisted by molecular chaperones in attaining its precise f