Intrinsically Disordered Regions of Human Plasma Membrane Proteins Preferentially Occur in the Cytoplasmic Segment

Restriction of μM-calcium–requiring calp

Restriction of μM-calcium–requiring calpain activation to the plasma membrane in human neuroblastoma cells: Evidence for regionalized influence of a calpain activator protein

✍ Thomas B. Shea 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 111 KB 👁 1 views

Regulation of the mM-calcium-requiring form of calpain (m calpain) was studied in SH-SY-5Y human neuroblastoma cells. Immunoblot analysis demonstrated that the vast majority of m calpain is localized within cytosolic pools. Calpain activation was monitored as a function of autolysis within intact ce