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Intrinsic asymmetries of amino acid enantiomers and their peptides: A possible role in the origin of biochirality

✍ Scribed by David W. Deamer; Reay Dick; Wolfram Thiemann; Meir Shinitzky


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
317 KB
Volume
19
Category
Article
ISSN
0899-0042

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The role of Asp-49 and other conserved a
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The role of aspartic acid49 (Asp-49) in the active site of porcine pancreatic phospholipase A2 was studied by recombinant DNA techniques: two mutant proteins were constructed containing either glutamic acid (Glu) or lysine (Lys) at position 49. Enzymatic characterization indicated that the presence