Intravitreal administration of the anti-TNF monoclonal antibody Infliximab in the rabbit
β Scribed by Panagiotis G. Theodossiadis; Vasilios S. Liarakos; Petros P. Sfikakis; Alexander Charonis; Georgios Agrogiannis; Nikolaos Kavantzas; Ioannis A. Vergados
- Publisher
- Springer-Verlag
- Year
- 2008
- Tongue
- English
- Weight
- 355 KB
- Volume
- 247
- Category
- Article
- ISSN
- 0065-6100
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
BALB/c mice were immunized against syngeneic murine 79 I T136 monoclonal antibody (MAb) by intraperitoneal (i.p.) injection of the antibody conjugated to ricin toxin A chain. Subsequently, in these and control mice. the biodistribution of radioiodinated 79 I T/36 antibody and isotype-matched (IgGlb)
## Abstract Monoclonal antiβLytβ1.1 alloantibody was produced as tissue culture supernatant and administered to mice. The antibody, given intraperitoneally, resulted in the suppression of all T cell functions studied, but was without direct effect on B cells. Thus, skin and tumor allograft survival
We have previously shown that injection of adult rabbits with anti-immunoglobulin (Ig) antibody (Ab) induces the expression of genetically unexpected Ig markers, ie., a1 allotypic determinants. We now show that these rabbit Ig markers can also be induced in mice by a similar treatment; in the latter