Intravenous pharmacokinetics, oral bioavailability and dose proportionality of ragaglitazar, a novel PPAR-dual activator in rats

Pharmacokinetics of SDZ 64-412, a novel

Pharmacokinetics of SDZ 64-412, a novel antiasthmatic agent, following intravenous, oral, and inhalation dosing in the rat

✍ Steven B. Charnick; Zhiling Yu; Lawrence V. Athill; Adel H. Karara; Francis L. S 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 496 KB 👁 1 views

The pharmacokinetics of SDZ 64412, an antiasthmatic agent, were investigated following intravenous, oral, and inhalation dosing in rats. 14C-SDZ 64-412 was administered intravenously (2.75 mg kg-') and orally (5.5 mg kg-', 110 mg kg-I), whereas nohradiolabeled drug (5.04 mg kg-') was-administered us