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Intravenous immunoglobulin and Anti-D in Idiopathic Thrombocytopenic Purpura (ITP): Mechanisms of Action

โœ Scribed by Lazarus, Alan H; Freedman, John; Semple, John W

Book ID
123435359
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
57 KB
Volume
19
Category
Article
ISSN
0955-3886

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Specific and nonspecific mechanisms of a
Specific and nonspecific mechanisms of action of immunoglobulin G in therapy of idiopathic thrombocytopenic purpura (ITP)
โœ Jungi, T. W. ;Imbach, P. ;Barandun, S. ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› Springer-Verlag โš– 474 KB

The efficacy of IgG infusion therapy in ITP is now established even in cases resistant to other forms of therapy. However, the mechanism of action is still speculative. We assume that a correction of the elevated thrombocyte clearance is brought about at several levels. First, antibodies specific fo