## Abstract ## Background Efficient tumor targeting of polymeric gene transfer systems (polyplexes) represents a major challenge. To establish tumor targeting after intravenous (IV) administration, the circulation lifetime of these systems should be sufficiently long. Since naked polyplexes are ra
โฆ LIBER โฆ
Intravenous fate of poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes
โ Scribed by Ferry Verbaan; Inger van Dam; Yoshinubu Takakura; Mitsuru Hashida; Wim Hennink; Gert Storm; Christien Oussoren
- Book ID
- 113591240
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 160 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0928-0987
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Steric stabilization of poly(2-(dimethyl
โ
F. J. Verbaan; C. Oussoren; C. J. Snel; D. J. A. Crommelin; W. E. Hennink; G. St
๐
Article
๐
2004
๐
John Wiley and Sons
๐
English
โ 231 KB
Freeze-Drying of Poly((2-dimethylamino)e
โ
Jong-Yuh Cherng; Petra van de Wetering; Herre Talsma; Daan J. A. Crommelin; Wim
๐
Article
๐
1997
๐
Springer US
๐
English
โ 323 KB
Sterilization of poly(dimethylamino) eth
โ
Gert W Bos; Ana Trullas-Jimeno; Wim Jiskoot; Daan J.A Crommelin; Wim E Hennink
๐
Article
๐
2000
๐
Elsevier Science
๐
English
โ 216 KB
Fast, multi-responsive microgels based o
โ
Jan M.D. Heijl; Filip E. Du Prez
๐
Article
๐
2004
๐
Elsevier Science
๐
English
โ 211 KB
Structure investigation of poly((2-dimet
โ
Wonjoo Lee; Peter Kofinas; R.M. Briber
๐
Article
๐
2012
๐
Elsevier Science
๐
English
โ 625 KB
Comparative transfection studies of huma
โ
Petra van de Wetering; Nancy M.E. Schuurmans-Nieuwenbroek; Wim E. Hennink; Gert
๐
Article
๐
1999
๐
John Wiley and Sons
๐
English
โ 169 KB
๐ 2 views
Background Poly(2-(dimethylamino)ethyl methacrylate) (p(DMAEMA)) can be used successfully for in vitro transfection of different cell lines, including the OVCAR-3 human ovarian carcinoma cell line. The aim of this study was to investigate whether it is possible to transfect OVCAR-3 cells in vivo wit