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Intravenous cocaine and heroin self-administration in rats selectively bred for differential saccharin intake: phenotype and sex differences

✍ Scribed by Marilyn E. Carroll; Andrew D. Morgan; Wendy J. Lynch; Una C. Campbell; Nancy K. Dess

Publisher: Springer
Year: 2002
Tongue: English
Weight: 86 KB
Volume: 161
Category: Article
ISSN: 0033-3158
DOI: 10.1007/s00213-002-1030-5

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## Rationale Evidence suggests that responsiveness to a drug-paired cue is predicted by the reinforcing magnitude of the drug during prior self-administration. It remains unclear, however, if this principle holds true when comparisons are made across drug reinforcers. ## Objective The current stu