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Intravenous administration of melatonin reduces the intracerebral cellular inflammatory response following transient focal cerebral ischemia in rats

✍ Scribed by Ming-Yang Lee; Yu-Hsiang Kuan; Hung-Yi Chen; Tsung-Ying Chen; Shur-Tzu Chen; Chien-Chih Huang; I-Ping Yang; Yun-Shang Hsu; Tian-Shung Wu; E-Jian Lee


Book ID
111264423
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
803 KB
Volume
42
Category
Article
ISSN
0742-3098

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## Abstract Unfractionated heparin (UH) decreases the extent of infarction after transient focal brain ischemia in the rat and abridges neuroinflammatory damage in patients with acute stroke. This study was aimed at assessing whether controlled and steady heparinemia in plasma can reduce infarct vo