To examine the effect of alendronate (4-amino-1-hydroxybutylidene bisphosphonate) on fracture repair, the drug was given to mature beagle dogs orogastrically at 2 mg/kg/day for 9 weeks preceding fracture. 16 weeks after fracture, or both before and after fracture (25 weeks). A transverse mid-diaphys
β¦ LIBER β¦
Intravenous Administration of Alendronate Counteracts the In Vivo Effects of Glucocorticoids on Bone Remodeling
β Scribed by F. Falcini; S. Trapani; M. Ermini; M. L. Brandi
- Publisher
- Springer
- Year
- 1996
- Tongue
- English
- Weight
- 346 KB
- Volume
- 58
- Category
- Article
- ISSN
- 1432-0827
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## Abstract Patients at high risk for osteoporosis and its associated morbidity, including postmenopausal women, are being pharmacologically managed to stabilize and improve bone mass. Alendronate sodium (Fosamaxβ’) is a commonly used antiresorptive agent effective in osteopenic women for reducing b
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