Intravenous administration of 2,7,8-trimethyl-2-(β-carboxyethyl)-6-hydroxy chroman (γ-CEHC) to rats and determination of its plasma concentration and urinary sodium excretion

Occurrence and Determination of a Natriu

Occurrence and Determination of a Natriuretic Hormone, 2,7,8-Trimethyl-2-(β-carboxyethyl)-6-hydroxy Chroman, in Rat Plasma, Urine, and Bile

✍ Akihiro Hattori; Takeshi Fukushima; Kazuhiro Imai 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 96 KB

The occurrence of a new natriuretic hormone, 2,7,8trimethyl-2-(␤-carboxyethyl)-6-hydroxy chroman (LLU-␣, ␥-CEHC) in rat plasma was demonstrated and its concentration was determined using a coupled-column HPLC with a fluorometric derivatization with 4-N,Ndimethylaminosulfonyl-7-piperazino-2,1,3-benzo