Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure
โ Scribed by Johanos, Andrew M.
- Book ID
- 123412571
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 139 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0736-4679
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The influence of acetylcysteine, administered at presentation to hospital, on the subsequent clinical course of 100 patients who developed paracetamol-induced fulminant hepatic failure was analysed retrospectively. Mortality was 37% in patients who received acetylcysteine 10-36 h after the overdose,
Background. When administered early after an overdose of acetaminophen, intravenous acetylcysteine prevents hepatic necrosis by replenishing reduced stores of glutathione. How acetylcysteine improves the survival of patients with established liver damage induced by acetaminophen, however, is unknown