Intravascular radiopaque catheters in the dog: Tissue reaction and possible lead loss
✍ Scribed by Winders, Robert L. ;Rostorfer, Howard H. ;Blackschaffer, Bernard C.
- Book ID
- 102871548
- Publisher
- John Wiley and Sons
- Year
- 1973
- Tongue
- English
- Weight
- 810 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0021-9304
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✦ Synopsis
Abstract
Male mongrel dogs were divided into two groups and placed in urine collection cages for 24‐hr urine samples. One group was implanted with sterile radiopaque polyethylene catheter and stainless steel guide wire fragments in the venous vasculature via an incision in the left femoral vein and the remaining group in the arterial vasculature via the left femoral artery. The catheter fragments, made radiopaque by an admixture of 25% lead oxide and 75% polyethylene, were located by roentgenograms and along with the guide wire fragments removed at necropsy 18–46 weeks following implantation. Gross and microscopic tissue lesions consisted of fibrous tissue tubes and slings which completely enclosed and anchored the fragments and intimal hyperplasia with fibrous tissue organization of thrombi, respectively. Tissue staining techniques for lead, catheter fragment weights, blood lead levels, and urine lead content all revealed no evidence of lead loss from the catheter fragment implants.