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Intravascular adenosine: the endothelial mediators of its negative dromotropic effects

✍ Scribed by Rafael Rubio; Guillermo Ceballos; Eduardo Balcells

Book ID
114017045
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
447 KB
Volume
370
Category
Article
ISSN
0014-2999

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## Abstract Methotrexate remains the mainstay of therapy for rheumatoid arthritis yet its mechanism of action remains unclear. Recent work from our laboratory indicates that methotrexate promotes increased adenosine release from cells and tissues and that the anti‐inflammatory actions of methotrexa