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Intrauterine onset of a mononeuropathy: Peroneal neuropathy in a newborn with electromyographic findings at age one day compatible with prenatal onset

✍ Scribed by H. Royden Jones Jr; Gerald J. Herbison; Stanley R. Jacobs; Peter R. Kollros; George A. Macones


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
346 KB
Volume
19
Category
Article
ISSN
0148-639X

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✦ Synopsis


Mononeuropathies are unusual at birth, and electromyographic (EMG) definition the first day of life has not been reported previously. Although neonatal mononeuropathies may be related to obstetric complications, prenatal mechanisms also merit consideration. We report an infant, born with a peroneal neuropathy, whose EMG was performed 18 h after birth. An isolated peroneal nerve lesion with lack of compound muscle action potential and the presence of fibrillation potentials, confined to the tibialis anterior muscle, suggested a primary intrauterine mechanism for this mononeuropathy. Because of an infant's small size, the temporal profile used in adults for appearance of EMG signs of wallerian degeneration may not apply. Inaccurate conclusions may result if the EMG standards for timing adult nerve injury are applied to newborns. To our knowledge, previous published cases of neonatal mononeuropathies have not included babies whose first EMG was performed before age 4 days. Therefore, an EMG study shortly after birth needed to be accomplished if strong support for the hypothesis of a prenatal onset were to be generated. Our findings are compatible with an intrauterine onset of this baby's peroneal neuropathy.