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Intrauterine lethality of trisomy 21 fetuses with increased nuchal translucency thickness

✍ Scribed by J. A. Hyett; N. J. Sebire; R. J. M. Snijders; Professor K. H. Nicolaides


Book ID
114433338
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
283 KB
Volume
7
Category
Article
ISSN
0960-7692

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This study examines GATA-4 gene expression in cardiac tissue from fetuses with trisomy 21 presenting with increased nuchal translucency thickness at 10-14 weeks of gestation. mRNA was extracted from cardiac tissue after termination of pregnancy at 10-18 weeks of gestation in ten trisomy 21 fetuses a

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In a multicenter screening study for trisomy 21 involving ultrasonographic measurement of fetal nuchal translucency thickness (NT) at 10-14 weeks of gestation, 100,311 singleton pregnancies with a live fetus were examined. There were 46 cases of trisomy 13, and in 33 (72%) of these, the NT was above