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Intratumor heterogeneity and chemotherapy-induced changes in EGFR status in non-small cell lung cancer

✍ Scribed by Jan Nyrop Jakobsen; Jens Benn Sørensen

Publisher
Springer
Year
2011
Tongue
English
Weight
332 KB
Volume
69
Category
Article
ISSN
0344-5704

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## Abstract Mounting evidence has suggested somatic mutations in the __EGFR__ gene are associated with better responsiveness to __EGFR__ tyrosine kinase inhibitors (TKIs) in patients with non‐small‐cell lung cancer (NSCLC). Some, but not all, studies have reported that the mutations were more frequ