Intrathecal vasoactive intestinal polypeptide modulates spinal reflex excitability primarily to cutaneous thermal stimuli in rats

Intrathecal galanin at low doses increas

Intrathecal galanin at low doses increases spinal reflex excitability in rats more to thermal than mechanical stimuli

✍ Z. Wiesenfeld-Hallin; M. J. Villar; T. Hökfelt 📂 Article 📅 1988 🏛 Springer-Verlag 🌐 English ⚖ 345 KB

The neuropeptide galanin (GAL) was injected intrathecally (i.t.) in decerebrate, spinalized, unanesthetized rats and its effect on the nocifensive flexor reflex was examined. The reflex, which was evoked by intense mechanical or thermal stimulation of the foot, was recorded from the ipsilateral hams