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Intrathecal IgM synthesis is a prognostic factor in multiple sclerosis

✍ Scribed by Luisa M. Villar; Jaime Masjuan; Pedro González-Porqué; José Plaza; María C. Sádaba; Ernesto Roldán; Alfredo Bootello; José C. Alvarez-Cermeño


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
92 KB
Volume
53
Category
Article
ISSN
0364-5134

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Clinical parameters and intrathecal IgG
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In a search for early prognostic features in multiple sclerosis, the progression rate was calculated in 200 consecutive multiple sclerosis patients who had had a lumbar puncture, and correlated with age at onset, type of disease course, the patient's sex, as well as with indices of blood-brain barri

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✍ M. Poloni; B. Rocchelli; R. Scelsi; P. Pinelli 📂 Article 📅 1979 🏛 Springer 🌐 English ⚖ 746 KB

Intrathecal IgG synthesis has been investigated by determining the IgG index and by isoelectric focusing in 30 cases of definite multiple sclerosis, in 15 cases of probable multiple sclerosis and in 128 patients affected by other neurological diseases. The blood-brain barrier function was evaluated