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Intraspinal release of substance P and calcitonin gene-related peptide during opiate dependence and withdrawal

โœ Scribed by Mouton, C.R.; Hutchison, W.D.; Hendry, I.A.

Book ID
122842943
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
759 KB
Volume
43
Category
Article
ISSN
0306-4522

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โœ G. K. L. Tiong; T. L. Pierce; J. E. Olley ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 589 KB

Substance P (SP) and calcitonin gene-related peptide (CGRP) are putative transmitters in the central and peripheral (sensory) nervous systems. In this study, we examined the effects of dependence on and withdrawal from morphine and methadone on brain SP and CGRP content. Female Long Evans rats (70-1