Intraspecies transfer via total cellular DNA of the gene for hypoxanthine phosphoribosyltransferase into cultured mouse cells

DNA-mediated transfer of the mouse gene

DNA-mediated transfer of the mouse gene for hypoxanthine phosphoribosyltransferase into cultured mouse cells: No integration of the transferred gene at its homologous site in the host genome

✍ Willecke, Klaus ;Klomfaß, Marion ;Schäfer, Reinhold 📂 Article 📅 1981 🏛 Springer 🌐 English ⚖ 767 KB

An established Chinese hamster cell line was fused with microcells isolated from phen0typically stable transferent mouse cells which contained a mouse transgenome coding for an abnormal form of mouse hypoxanthine phosphoribosyltransferase (HPRT, EC. No. 2.4.2.8) (Willecke et al. 1979). Two hybrids w