✦ LIBER ✦
Intrarectal metronidazole in the prevention of anaerobic infections after emergency appendicectomy: A controlled clinical trial
✍ Scribed by J. Rodgers; D. Ross; W. McNaught; G. Gillespie
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- English
- Weight
- 274 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0007-1323
No coin nor oath required. For personal study only.
✦ Synopsis
Summary
A series of 102 patients with presumptive acute appendicitis entered a prospective, randomized, clinical trial of intrarectal metronidazole given over a 48-h period commencing before surgery. Adequate levels of circulating metronidazole were achieved. A significant reduction in the incidence of anaerobic wound infection was observed in the treated group (P < 0.02). The convenience and short duration of the prophylactic regimen allowed early discharge from hospital. No untoward effects were observed.