Intraprotein electron transfer in inducible nitric oxide synthase holoenzyme
β Scribed by Changjian Feng; Andrea L. Dupont; Nickolas J. Nahm; Donald E. Spratt; James T. Hazzard; J. Brice Weinberg; J. Guy Guillemette; Gordon Tollin; Dipak K. Ghosh
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 367 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1432-1327
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## Abstract Free radical nitric oxide (NO), generated by inducible nitric oxide synthase (iNOS) in astrocytes and macrophages, has been implicated in CNS inflammatory disorders such as multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE). Mycophenolic acid (MPA),