Intrapleural tetracycline in malignant pleural effusions: A randomized study
โ Scribed by Arlene J. Zaloznik; Stephen G. Oswald; Michael Langin
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 309 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## BACKGROUND. The purpose of this study was to compare the effectiveness and safety of a chronic indwelling pleural catheter with doxycycline pleurodesis via tube thoracostomy in the treatment of patients with recurrent symptomatic malignant pleural effusions (MPE). ## METHODS. In this multi-i
## HE NATURE OF PLEURAL EFFUSIONS has been T extensively explored by means of biochemical, bacteriological, and histological methods, and all are currently employed to distinguish their benign or malignant character. Criteria for differentiation moreover are based upon certain definitive clinical
## BACKGROUND. Treatment of patients with malignant pleural effusions is mostly palliative. Tetracycline and bleomycin are the two most commonly used agents for the treatment of pleurodesis. In this study, the authors used a combination of the two drugs for this particular purpose. ## METHODS.
Telomerase activity in 16 pleural effusions was studied using an in situ telomerase repeat amplification protocol (TRAP) assay on cytospin preparations. Six of nine cytologically malignant specimens contained telomerase-positive cells (67%), and in two further specimens, suspicious positive cells we