Intrapleural application of recombinant interleukin-2 in patients with malignant pleurisy due to lung cancer
โ Scribed by Kosei Yasumoto; Takeshi Ogura
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 424 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0921-299X
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Preclinical data suggest synergy of interleukin-2 (IL-2) combined with alphainterferon (IFN). In addition, toxicities of IL-2 may be decreased by intermittent continuous infusion. The purpose of this trial was to determine the maximum tolerated dose (MTD) of recombinant IL-2 combined with alpha-IFN