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Intraorally fast-dissolving particles of a poorly soluble drug: Preparation and in vitro characterization

✍ Scribed by Riikka Laitinen; Eero Suihko; Kaisa Toukola; Mikko Björkqvist; Joakim Riikonen; Vesa Pekka Lehto; Kristiina Järvinen; Jarkko Ketolainen


Book ID
116438081
Publisher
Elsevier Science
Year
2009
Tongue
French
Weight
614 KB
Volume
71
Category
Article
ISSN
0939-6411

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Precipitation of a poorly soluble model
✍ Philip J. Sassene; Matthias M. Knopp; Janne Z. Hesselkilde; Vishal Koradia; Anne 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 311 KB

Precipitation of cinnarizine during in vitro lipolysis of a self-microemulsifying drug delivery system (SMEDDS) was characterized to gain a better understanding of the mechanisms behind the precipitation. During in vitro lipolysis of the SMEDDS with or without cinnarizine, samples were taken at seve