Intraoperative Secretion of Intact Parathyroid Hormone and Amino-Terminal Parathyroid Hormone Fragments from Normal Parathyroid Glands Associated with Solitary Parathyroid Adenoma

Intact insulin-like growth factor bindin

Intact insulin-like growth factor binding protein-5 (IGFBP-5) associates with bone matrix and the soluble fragments of IGFBP-5 accumulated in culture medium of neonatal mouse calvariae by parathyroid hormone and prostaglandin E2-treatment

✍ Yoshiyuki Hakeda; Hiroshi Kawaguchi; Marja Hurley; Carol C. Pilbeam; Christine A 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 668 KB

We examined the distribution of insulin-like growth factor binding proteins (IGFBPs) in cultured neonatal mouse calvariae. IGFBP-3 and -4 were predominantly found in the conditioned medium. IGFBP-2 was partitioned between conditioned medium and bone and extracellular matrix (BECM), while intact (31