Intraoperative localization of neuroblastoma in children with 123I- or 125I-radiolabeled metaiodobenzylguanidine
✍ Scribed by Hélène Martelli; Marcel Ricard; Michèle Larroquet; Michel Wioland; François Paraf; Monique Fabre; Patrice Josset; Pierre G. Helardot; Frédéric Gauthier; Marie-Josée Terrier-Lacombe; Jean Michon; Olivier Hartmann; Marie Dominique Tabone; Catherine Patte; Jean Lumbroso; Max Grüner
- Book ID
- 117221147
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 55 KB
- Volume
- 123
- Category
- Article
- ISSN
- 0039-6060
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Our experience in scintigraphic diagnosis using 123I/131I-metaiodobenzylguanidine (MIBG) on 37 children with neuroblastomas stage III-IV is reported and discussed, together with the results obtained by other authors on MIBG diagnosis at the International Workshop of Pediatric Oncology held in Rome i
## Abstract ## BACKGROUND During radiolabeled metaiodobenzylguanidine (MIBG) administration in children with neuroblastoma, the thyroid is protected from ^123/131^I uptake by potassium iodide. Despite this protection, up to 64% of patients develop thyroid dysfunction. The authors introduce a new m