Sixty-four patients with recurrent or metastatic colorectal cancer underwent radioimmunoguided surgery (RIGS). Thirty patients (Group A) were preoperatively injected with radiolabeled monoclonal antibody (MAb) B72.3, a whole IgG1 that reacts with tumor-associated glycoprotein (TAG-72) antigen. Thirt
Intraoperative localization of colorectal cancers using radiolabelled monoclonal antibodies
โ Scribed by Mr. B. R. Davidson; W. A. Waddington; M. D. Short; P. B. Boulos
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 783 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0007-1323
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## BACKGROUND. The authors showed previously that radiolabeled monoclonal antibody (MoAb) and a hand-held, gamma-detecting probe can be used to localize tumor-reactive lymph nodes in vivo. The authors examined the feasibility, safety, and biologic effects of cellular immunotherapy using autologous
The in vivo post-targeting of tumor by means of anti-carcinoembryonic-antigen (CEA) monoclonal antibodies (MAbs) and the avidin-biotin three-step system was tested by immunoscintigraphy and radioimmunoguided surgery (RIGS) in six patients with primary or recurrent rectal cancer. The patients were pr
## Abstract The monoclonal antibodies LICR-LON M8 and 77-1, which react with epithelial membrane antigen, showed a strong reaction with colorectal cancer on immunohistochemistry. In a radioimmunolocalization study in patients with colorectal cancer, 111In-labelled M8 detected 13 of 16 tumour sites