Intraoperative cytology of lymph nodes and lymphoid lesions

✍ Scribed by James A. Wilkerson

• Publisher: John Wiley and Sons
• Year: 1985
• Tongue: English
• Weight: 613 KB
• Volume: 1
• Category: Article
• ISSN: 8755-1039
• DOI: 10.1002/dc.2840010111

✦ Synopsis

Cytologic preparations from lymph nodes and lymphoid krions in other tissues permit accurate intraoperative diag-

ofa number of lesions that are not commonly identijiable with certainty in convenrional frozen sections. The clarity of c.ytologic detail in smears or imprints allows recognition of Hodgkin's and non-Hodgkin's lymphomas, certain metastatic tumors such as melanoma or oaf cell carcinoma, and some notineoplastic disorders. all of which must be diagnosed on the hizsis of cellular alterations. The characteristic cytologic features of'these disorders are presented.

Cytologic preparutions also have proved valuable in evaluating lesions that usually can be diagnosed with .frozen sections. For these lesions. the ability to see cytologic details provides greater diagnostic certainty. For Some necrotic, calcified, or Juttv sper.imens, smears or imprints are the only preparations possible. With alcohol Jixation and rapid hematoxylin and eosin or Papanicolaou staining, the preparations are ready for enmmittotion within 2 minutes after the specintens are received. The cytologic presentations are essentially identical to those of aspiration biopsies. Use of each type of preparation helps develop and maintain the diagnostic skills needed for the other.