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Intraocular tolerance and pharmacokinetics of polyanhydrides loaded with 5-fluorouracil

✍ Scribed by J.C. Pastor; M.I. López; A. Pampliega; A. Alberola


Book ID
115894821
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
137 KB
Volume
55
Category
Article
ISSN
0014-4835

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## Abstract The pharmacokinetic parameters of 5‐fluorouracil were compared after intravenous administration at a dose of 30 mg/kg to control Sprague–Dawley rats and to rats with diabetes mellitus induced by streptozotocin (DMIS). In DMIS rats, the area under the plasma concentration–time curve from