Intranuclear aluminum content in Alzheimer's disease, dialysis encephalopathy, and experimental aluminum encephalopathy
โ Scribed by D. R. Crapper; S. Quittkat; S. S. Krishnan; A. J. Dalton; U. Boni
- Publisher
- Springer-Verlag
- Year
- 1980
- Tongue
- English
- Weight
- 636 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0001-6322
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The use of inductively coupled plasma source mass spectrometry (ICP-MS) for multi-element analysis has led to the observation, in two separate studies, of increased blood tin in Alzheimer's disease (AD). We have therefore applied the technique of ICP-MS to hippocampal tissues obtained post-mortem fr
## Abstract It is well established that aluminum (Al) is a neurotoxic agent that induces the production of free radicals in brain. Accumulation of free radicals may cause degenerative events of aging such as Alzheimer's disease. On the other hand, melatonin (Mel) is a known antioxidant, which can d