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Intraneural reticular perineurioma of the hypoglossal nerve

✍ Scribed by Yoon Seup Kum; Jeong Kyu Kim; Chang Ho Cho; Ho Kyun Kim

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
267 KB
Volume
31
Category
Article
ISSN
1043-3074

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✦ Synopsis

Abstract

Background.

Intraneural perineurioma or reticular perineurioma, which is 1 variant of extraneural perineurioma, has been rarely reported in the head and neck region.

Methods.

We report a case of a 52‐year‐old woman who wasseen with a swelling in the neck. A mass was found located on the medial aspect of the left submandibular gland and was palpated with a sponge‐like texture. The mass was seen as a homogenous semisolid lesion on CT and ultrasound examination.

Results.

Surgical exploration revealed expansion of the hypoglossal nerve. Microscopically, the tumor showed both pseudo‐onion bulb, which is a feature of intraneural perineurioma, and reticular pattern with microcysts, which is a feature of reticular variant of extraneural perineurioma. The tumor cells were immunopositive for epithelial membrane antigen and human erythrocyte glucose transporter‐1 (GLUT‐1).

Conclusion.

An intraneural reticular perineurioma of the hypoglossal nerve should be included in the differential diagnosis of submandibular swelling. Β© 2008 Wiley Periodicals, Inc. Head Neck, 2009

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