Intranasal sumatriptan for the acute treatment of migraine
✍ Scribed by R. Salonen; E. Ashford; C. Dahlöf; R. Dawson; N. E. Gilhus; V. Lüben; D. Noronha; J. M. Warter
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 600 KB
- Volume
- 241
- Category
- Article
- ISSN
- 0340-5354
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Migraine is a common, multisymptom disorder that can severely impact the daily activities of migraineurs. Triptans (primarily sumatriptan) are the most commonly prescribed treatment for migraine and are considered a relatively safe and effective initial therapy. Unfortunately, current sumatriptan fo
We have successfully obtained sumatriptan transdermal systems with different polymer compositions: methyl cellulose (MC), polyvinyl pyrrolidone (PVP) and a polyvinyl pyrrolidone (PVP)-polyvinyl alcohol (PVA) mixture. The systems contained 1,2-propylenglycol (MC) or sorbitol as a plasticizer (PVP and