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Intranasal nerve growth factor enhances striatal neurogenesis in adult rats with focal cerebral ischemia

✍ Scribed by Zhu, Wusheng; Cheng, Songming; Xu, Gelin; Ma, Minmin; Zhou, Zhiming; Liu, Dezhi; Liu, Xinfeng


Book ID
120370278
Publisher
Informa plc
Year
2011
Tongue
English
Weight
792 KB
Volume
18
Category
Article
ISSN
1071-7544

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## Abstract Increasing age decreases the number of new neurons in the dentate gyrus and the subventricular zone (SVZ). Sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor, enhances neurogenesis in young rats. The present study tested the hypothesis that sildenafil augments neurogenesis in aged