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Intranasal cowpox virus infection of the mouse as a model for preclinical evaluation of smallpox vaccines

✍ Scribed by Audrey Ferrier-Rembert; Robert Drillien; Jean-Nicolas Tournier; Daniel Garin; Jean-Marc Crance

Book ID
116959744
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
570 KB
Volume
25
Category
Article
ISSN
0264-410X

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## Abstract A temperature‐sensitive mutant virus unable to replicate at 38Β°C was recovered from passage 189 (IVpi‐189) of Madin‐Darby canine kidney cells infected persistently with influenza A. Immunofluorescent staining of the IVpi‐189 virus‐infected cells revealed disrupted transport of the matri