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Intramolecular Wittig Reaction: A New Synthesis of (S)-Pyrrolam A

✍ Scribed by Majik, Mahesh S. (author);Parameswaran, Perunninakulath S. (author);Tilve, Santosh G. (author)


Publisher
John Wiley and Sons
Year
2008
Tongue
German
Weight
154 KB
Volume
91
Category
Article
ISSN
0018-019X

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✦ Synopsis


Abstract

A straightforward synthesis of (S)‐pyrrolam A is described. The synthesis involves in situ generation of the phosphorane 3, followed by an intramolecular Wittig reaction to furnish (S)‐pyrrolam A.


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A new synthesis of imidazolinones and quinazolinones by intramolecular aza-Wittig reaction is described. 3, 6, lo, Readily available azido substituted imides and 12 reacted with triphenylphosphine tributvlnhosoh&e to afford thecorresoondins imidazolinones 1. 7 aZa' quinazolinones 2, 12 via the Sta