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Intramolecular ring closure of α,β-epoxy sulfoxides with hydroxyl group: A novel synthesis of 2-acyl cyclic ethers and 3-keto cyclic ethers

✍ Scribed by Tsuyoshi Satoh; Ken-ichi Iwamoto; Koji Yamakawa


Publisher
Elsevier Science
Year
1987
Tongue
French
Weight
231 KB
Volume
28
Category
Article
ISSN
0040-4039

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✦ Synopsis


Exo-trigonal-type intramolecular ring closure of the cf,8-epoxy sulfoxides with hvdroxvl group cave 2-acvl cyclic ethers (5. 6. and 13 membered rings) in good-yields.-

In contrast to this, endo-trigonalltype ring closure of the a,8-epoxy sulfoxides was rather difficult.

Recently, cyclic ethers have received much attention regarding synthetic organic chemistry.

They are found in many natural products having remarkable