Intramolecular Radical Cyclization of 2-Haloethanal Allyl Acetal and Allyl 2-Halophenyl Ether with a Grignard Reagent in the Presence of Iron(II) Chloride

✍ Scribed by Yasuhiro Hayashi; Hiroshi Shinokubo; Koichiro Oshima

• Book ID: 104258455
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 518 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(97)10489-0

✦ Synopsis

Treatmentof 2-iodoethamdatkenylacetals,generatedby iodaetherization frnmbntyl vinyl ether and atlytic atmhols, with phenylmagnesinm bromide in the presence of a catafytk amount of FeC12 provided tetrahydrofuranderivatives in good yietds. At]yi 2-hafophenyl dh=S dSO fiOdXt dihydmbenzofnran derivativesupontreatment withphenybnagnesinmbro midenndm FeCf2eatafysis.