Intramolecular nitrile oxide cycloaddition (INOC) of substituted amido-oximes
β Scribed by Ugo Chiacchio; Antonino Corsaro; Vito Librando; Antonio Rescifina; Roberto Romeo; Giovanni Romeo
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- French
- Weight
- 642 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0040-4020
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## Abstract For Abstract see ChemInform Abstract in Full Text.
## Abstract Cycloaddition of nitrile oxides to substituted vinylphosphonates was performed. A series of 4,5βdihydroisoxazoles containing phosphonyl group were synthesized under very mild condition in excellent regiospecificity. Β© 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:309β311, 2003; Publis
Intramolecular nitrile oxide cycloaddition to functionalized furans occurs with complete regiochemical control but low diastereoselectivity. The poor reactivity of furan as 2 3Z component in the 1,3-dipolar cycloaddition with nitrile oxide' greatly limited its practical use in this reaction. 2,3 Thi