The efficiency of intramolecular general
โ
Anthony J. Kirby; Koh Lip Lin
๐
Article
๐
1978
๐
Elsevier Science
๐
French
โ 114 KB
There is good evidence that intramolecular general base catalysis is much less efficient than intramolecular nucleophilic catalysis.' It has recently been suggested' that this is true only for reactions in aqueous solvents, and that in nonaqueous solvents -and perhaps also in enzyme active sites fro