Intramolecular Friedel-Crafts alkylation promoted by the cross conjugated β-keto ester system. An efficient approach to highly functionalized hydrophenanthrenes and hydrochrysenes

✍ Scribed by Hsing-Jang Liu; Duong Duc-Phi Tran

• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 231 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)00658-9

✦ Synopsis

The cross conjugated ~-keto ester system was shown to be an excellent promoter for the intramolecular Friedel-Crafts alkylation to facilitate the rapid construction of highly functionalized phenanthrene and chrysene derivatives.