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Intramolecular cyclization of amido acids into pyrrolidinothieno(or [1]benzothieno)[3]azepinediones

✍ Scribed by Mohamed Othman; Pierre Netchitailo; Bernard Decroix


Book ID
102345951
Publisher
Journal of Heterocyclic Chemistry
Year
1997
Tongue
English
Weight
442 KB
Volume
34
Category
Article
ISSN
0022-152X

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✦ Synopsis


Abstract

The synthesis of pyrrolidino[2,1‐b]thieno[3,2(2,3)‐f][3]azepinediones 7a,b and pyrrolidino[2,1‐b]‐[1]benzothieno[3,2(2,3)‐f][3]azepinediones 7c,d are described starting from thiophenes or [1]benzothio‐phenes acetic acids. Their selective reduction using triethylsilane led to the corresponding azepinones 17a‐d.


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