Intramolecular CH···O Hydrogen-bond mediated stabilization of a Cis-DPro imide-bond in a stereocontrolled heterochiral model peptide

Stabilization of a novel β-turn-like mot

Stabilization of a novel β-turn-like motif by nonconventional intramolecular hydrogen-bonding interactions in a model peptide incorporating β-alanine

✍ A. K. Thakur; R. Kishore 📂 Article 📅 2000 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 119 KB

The chemical synthesis and x-ray crystal structure analysis of a model peptide incorporating a conformationally adaptable unsubstituted ␤-Ala residue: Boc-␤-Ala-Acc 6 -OCH 3 (C 16 H 28 N 2 O 5 , molecular weight ϭ 328.41; 1) has been described. The peptide crystallized in the space group P2 1 2 1 2