Intramolecular amidoalkylation of chiral imines and iminium ions: Stereoselective synthesis of anti-1,2- and -1,3-aminoalcohols
✍ Scribed by Hideaki Hioki; Tatsuo Izawa; Makoto Yoshizuka; Rieko Kunitake; Shô Itô
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- French
- Weight
- 232 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0040-4039
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A new stereoselective formal synthesis of (À)-mesembrane has been achieved by intramolecular condensation of chiral amide and 1,3-cyclohexanedione moiety. The precursor amide was readily prepared by condensation of the corresponding chiral amine and acid. Condensation provided moderate ratios of ene