Intramolecular Alkynylcyclopropanation of Olefins Catalyzed by Bi(OTf)3: Stereoselective Synthesis of 1-Alkynyl-3-azabicyclo[3.1.0]hexanes
β Scribed by Kimihiro Komeyama; Natsuko Saigo; Motoyoshi Miyagi; Ken Takaki
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 304 KB
- Volume
- 121
- Category
- Article
- ISSN
- 0044-8249
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Synthesis of Chiral 1-Substituted Tetrahydroisoquinolines by the Intramolecular 1,3-Chirality Transfer Reaction Catalyzed by Bi(OTf)3. -Treatment of chiral amines of type (I), (III), and (V) with Bi(OTf)3 results in formation of optically active tetrahydroisoquinolines. The (E)/(Z) configuration of